Here are some of KEY research components we used as our ingredient advisory board.

Below is the summary of the studies, with references.

On teeth whitening/ cosmetic appearance improving formulas

Calcium-containing, sodium bicarbonate- based toothpaste formulations were shown by electron microscopy to smooth tooth enamel WITHOUT introducing new scratches.  In contrast, commercial whitening toothpaste removed similar scratches but also created NEW ONES. [1]

On hardening the teeth &  cavity protection

Calcium-containing dentifrices were shown by electron microscopy and hardness measurements to put MINERAL onto the surface of enamel and to HARDEN IT.  Conventional fluoride toothpaste did not. [1]

After 15 test cycles, using serial treatments with calcium- containing, bicarbonate toothpaste, surface roughness was REDUCED by more than 50% and peak height was reduced by two thirds. [1]

Secondary caries remain a problem limiting the longevity of those who have composite fillings. Calcium Phospate (NACP) had the highest enamel remineralization and it was significantly HIGHER than fluoride-releasing control group. It remineralized 4-FOLD that of a the fluoride-releasing control. [2]

and

Dental caries is a chronic infectious disease that results in the destruction of tooth tissue.  It  is caused by complex interaction of oral microorganisms in dental plaque, diet and a broad array of host factors that needs to be present for tooth decay to occur.

For interproximal plaque, the essential oil mouth rinse produced statistically significance reductions in total recoverable streptococci counts S. mutans counts of 69.9 % and 75.4%. [3a]

Exposure to a half-strength essential oil mouth rinse produced statistically significant reductions on all of the strains tested with percent reductions ranging from 85,74 % for S. gordonii to 99.77% for S. sobrinus when compared to the control study. [3b] The authors concluded that their study provided evidence that the essential oil mouthwash tested, significantly reduced the level of S. mutans, and demonstrated in situ bactericidal activity.

On low abrasiveness particle size on demineralized tooth enamel (teeth that already have problems)

High abrasive pasts results in the greatest wear. Medium-abrasive pastes (1.76 um +/- .85um) and acidic fluoride gels (2.46 +/- .72 um) showed greater wear than with a low- abrasive paste (.84  +/- .38 um).  Spot lesions should be brushed with oral hygiene products of low abrasivity. [4]  Celtic Sea Salt is  between 0.035 – 0.5 microns (um).

Are you relying on your desensitizing toothpaste formula to keep your teeth healthy?

Both fluoride and the desensitizing agents alone reduced erosion, but no additive effect was found.  Combinations of fluoride and KNO3 did not reduce erosion. Desensitizing substances in toothpastes, alone or in combination, can reduce erosion, but is not valid for all formulas. [5]

Dental products containing calcium carbonate work to provide effective relief of sensitive teeth. [6]

Why we need MINERALS in our toothpaste

Samples of whole human enamel was analyzed by spark source mass spectrometer.  HIGH strontium concentrations levels in teeth of low caries (cavity) individuals  and LOW strontium concentrations were found in those who were high caries individuals.  Strontium STIMULATES CALCIUM DEPOSITION IN BONES AND TEETH.  Giving rats strontium in their diet increases the buildup of dentin in their teeth.[7]

French Celtic Sea Salt has naturally occurring levels of strontium. It is 1.8% minerals and trace elements.

Out of 35 inorganic elements, strontium was the only element found to be present in significantly lower amount in carious teeth.  [8]

The case against using bleaching gels

Bleaching gels cause enamel erosion. Hydrogen peroxide caused the most significant enamel erosion.  Hydrogen peroxide even with additives like calcium gluconate or fluoride still causes enamel erosion.  Basically, it’s a bad idea to whiten your teeth with bleaching gels. [9]

Sensitivity is thought to be due to the hydrogen peroxide molecules passing through the enamel and dentin into the pulp and causing pulpal inflammation [10]

The SLS problem… which is still found in “natural” toothpastes

SLS can remove the pellicle and a smear layer present on dentin. [11]

Toothpaste formulations without SLS could be favorable in preventing erosion.

References

1. Charig, Andrew; Winston, Anthony; Flickinger, Mark, (2004-09-01).Enamel mineralization by calcium-containing-bicarbonate toothpastes: assessment by various techniques. “ PMID:15645903.

2. Weir, M D; Chow, L C; Xu, H H K. “Remineralization of demineralized enamel via calcium phosphate nanocomposite. “ PMID:22933607.

3a. Yengopal, Veerasamy, (2004). ” Essential oils for caries prevention: A Viable option?” South Africa Dental Journal; 59: 296-298.

3b. Yengopal, Veerasamy, (2004). ” Essential oils for caries prevention: A Viable option?” South Africa Dental Journal; 59: 296-298.

4. A. M. Kielbassa, L. Gillmann, C. Zantner, H. Meyer-Lueckel, E. Hellwig, J. Schulte-Mönting, “Profilometric and Microradiographic Studies on the Effects of Toothpaste and Acidic Gel Abrasivity on Sound and  Demineralized Bovine Dental Enamel.”

5. M. T. Kato, M. Lancia, S. H. C. Sales-Peres, M. A. R. Buzalaf .“Preventive Effect of Commercial Desensitizing Toothpastes on Bovine Enamel Erosion in vitro.” Journal: Caries Research – CARIES RES , vol. 44, no. 2, pp. 85-89, 2010

6.  Petrou I, Heu R, Stranick M, Lavender S, Zaidel L, Cummins D, Sullivan RJ, Hsueh C, Gimzewski JK. A breakthrough therapy for dentin hypersensitivity: how dental products containing 8 % arginine and calcium carbonate work to deliver effective relief of sensitive teeth. J Clin Dent. 2009;20:23–31. [PubMed]

7. M. E. J. Curzon. “Strontium Content of Enamel and Dental Caries.” Journal: Caries Research – CARIES RES , vol. 11, no. 6, pp. 321-326, 1977

8. Manminder Riyat, D. C. Sharma. “Analysis of 35 Inorganic Elements in Teeth in Relation to Caries Formation.” Journal: Biological Trace Element Research – BIOL TR ELEM RES , vol. 129, no. 1, pp. 126-129, 2009.

9. Borges, Alessandra B.; Torres, Carlos R. G.; de Souza, Paulo A. B.; Caneppele, Taciana M. F.; Santos, Luciana F. T. F.; Magalhães, Ana CarolinaAre. “Bleaching Gels Containing Calcium and Fluoride: Effect on Enamel Erosion Susceptibility .” PMID:23193404.

10. Haywood VB. “History, safety and effectiveness of current bleaching techniques and application of night guard vital bleaching techniques.” Quint Inter.1992;27:471–488. [PubMed]

11. Parkinson CR. “Smear layer integrity and the role of surfactants.” J Dent Res.2007;86(Spec Iss B):188.

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